Human interleukin-4 antagonist/agonist screens
US5958707A · kind A · utility
12Cited by
0References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 30, 1995 |
| Grant date | Sep 28, 1999 |
| Priority date | — |
| Expiry date | May 30, 2015 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/5406
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Stably-transformed human cell lines containing a reporter gene operatively linked to an IL-4-responsive element are provided. In some embodiments a human Fc.sub..epsilon. RII IL-4-responsive element is used. In other embodiments a human germline .epsilon. transcript promoter is used as the responsive element. Also provided are methods for using such transformed cell lines to screen for agonists and/or antagonists of human interleukin-4.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.