Patent · US Expired

Orphan receptor

US5958710A · kind A · utility

7Cited by

14References

7Claims

0Family size

Assignee

Karo Bio AB · SE

Inventors

Georg Kuiper · Huddinge, SE
Eva L. K. Enmark · Tullinge, SE
Jan-Ake Gustafsson · Stockholm, SE

Key dates

Filing date	May 8, 1997
Grant date	Sep 28, 1999
Priority date	—
Expiry date	May 8, 2017

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P35/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention relates to a novel estrogen receptor-related nuclear receptor, hereinafter termed "ER.beta." having the amino acid sequence of FIGS. 1, 13A or 14A or substantially the same ambino acid sequence as the amino acid sequence shown in FIGS. 1, 13A or 13B or an amino acid sequence functionally similar to that sequence. The invention also relates to DNA sequences encoding the receptor. The receptor may be useful in isolating molecules for the treatment of disorders such as prostate cancer, benign prostatic hyperplasia, osteoporosis or cardiovascular disorders and in the testing of substances for estrogenic and other hormonal effects.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.