Chemical compounds
US5958971A · kind A · utility
1Cited by
1References
2Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Oct 22, 1997 |
| Grant date | Sep 28, 1999 |
| Priority date | — |
| Expiry date | Oct 22, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C311/51
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Prodrugs, of generic formula I, are disclosed for use in antibody directed enzyme prodrug therapy (ADEPT). The prodrugs are substrates for carboxypeptidase G2 (CPG2) and yield more active cytotoxic drugs than known products of CPG2 catalyzed reactions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.