Method for preparing a crystalline polymorph of terazosin monohydrochloride
US5959108A · kind A · utility
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4Claims
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Key dates
| Filing date | Jun 10, 1998 |
| Grant date | Sep 28, 1999 |
| Priority date | — |
| Expiry date | Jun 10, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A crystalline polymorphous terazosine monohydrochloride is obtained by suspending and treating a crystalline addition product of terazosine hydrochloride and methanol in a polar solvent which is an alcohol with 2 to 6 carbon atoms or a ketone with 2 to 6 carbon atoms or a mixture thereof. The thus obtained crystalline polymorphous terazosine hydrochloride is characterized by a reduced hygroscopicity and solvent residue retention capacity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.