Process for preparing 6-0-monoesters of castanospermine
US5959111A · kind A · utility
1Cited by
4References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 14, 1998 |
| Grant date | Sep 28, 1999 |
| Priority date | — |
| Expiry date | May 14, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a process for preparing a compound of formula (I): ##STR1## wherein R is C.sub.1 -C.sub.10 alkyl, phenyl or substituted phenyl, comprising treating a compound of formula (II): ##STR2## with bis(tributyltin) oxide in an organic solvent selected from the group consisting of o-xylene, m-xylene, p-xylene and mixed xylenes; and subsequently treating the reaction mixture with a compound of formula (III): ##STR3## wherein X is halogen and R is defined as above.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.