Process for the preparation of pure flupirtine maleate and its A modification

US5959115A · kind A · utility

Assignee

• Asta Medica Aktiengesellschaft · DE

Inventors

• Alfred Olbrich · Halle (Westf.), DE
• Peter Emig
• Bernhard Kutscher · Maintal, DE
• Karl-Friedrich Landgraf · Dresden, DE
• Siegfried Pauluhn · Walldürn, DE
• Hans Stange · Riesa, DE

Key dates

• Filing date: Apr 23, 1998
• Grant date: Sep 28, 1999
• Expiry date: Apr 23, 2018

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for preparation of pure flupertine maleate and the pure A crystalline form of flupertine maleate by the use of water soluble alcohols during synthesis and/or purification.