Production of optically active 2-substituted tetrahydropyran-4-ones
US5962282A · kind A · utility
1Cited by
2References
14Claims
0Family size
Inventors
Key dates
| Filing date | May 26, 1998 |
| Grant date | Oct 5, 1999 |
| Priority date | — |
| Expiry date | May 26, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P41/004
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Optically active 2-substituted tetrahydropyran-4-ols or esters thereof may be prepared using esterases or hydrolases from the corresponding racemic mixtures of esters or alcohols. This provides a route to the corresponding optically active ketones. The racemic mixtures are preferably in the cis-form. such mixtures may be produced by reacting but-3-ene-1-ol with an aldehyde in the presence of an acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.