Compositions and methods for the identification and synthesis of sialyltransferases

US5962294A · kind A · utility

Assignees

• The Regents of the University of California · US
• AMGEN INC. · US

Inventors

• James C. Paulson · West Hollywood, US
• Xiaohong Wen · San Diego, US
• Brian D. Livingston · San Diego, US
• William Gillespie · Culver City, US
• Sorge Kelm · Kiel, DE
• Alma L. Burlingame · Sausalito, US
• Katalin Medzihradszky · San Francisco, US

Key dates

• Filing date: Aug 4, 1993
• Grant date: Oct 5, 1999
• Expiry date: Aug 4, 2013

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/02
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

DNA isolates coding for sialyltransferase which contain a conserved region of homology and methods of obtaining such DNA are provided, together with expression systems for recombinant production of sialyltransferase.