Amino acid derivatives, medicaments containing said compounds and methods of producing them

US5962530A · kind A · utility

Assignee

• Dr. Karl Thomae GmbH · DE

Inventors

• Wolfhard Engel
• Wolfgang Eberlein · Biberach, DE
• Klaus Rudolf · Warthausen, DE
• Henri Doods · Warthausen, DE
• Heike-Andrea Wieland · Biberach, DE
• Klaus-Dieter Willim · Biberach an der Riß, DE

Key dates

• Filing date: May 29, 1998
• Grant date: Oct 5, 1999
• Expiry date: May 29, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The invention relates to new amino acid derivatives of general formula ##STR1## wherein R, U, V, Y, n, m and R.sup.1 to R.sup.3 are defined as in claim 1, their tautomers, diastereomers, enantiomers, mixtures thereof and salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable pharmacological properties, particularly selective NPY-antagonistic properties, pharmaceutical compositions containing these compounds, the use thereof and processes for preparing them.