Extruded multi-particulates
US5965161A · kind A · utility
362Cited by
123References
66Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 4, 1994 |
| Grant date | Oct 12, 1999 |
| Priority date | — |
| Expiry date | Nov 4, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/145
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A unit dose sustained-release oral dosage form containing a plurality of melt-extruded particles, each consisting essentially of a therapeutically active agent, one or more retardants, and an optional water-insoluble binder is disclosed. The particles have a length of from about 0.1 to about 12 mm and can be of varying diameters and each unit dose provides a release of therapeutically active agents over at least about 8 hours. Methods of preparing the unit doses as well as extrusion processes and methods of treatment are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.