Patent · US Expired

Method for improving optical purity of an amine compound

US5965432A · kind A · utility

32Cited by
1References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 12, 1997
Grant dateOct 12, 1999
Priority date
Expiry dateDec 12, 2017

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/83
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

There is provided a method for improving optical purity of an amine compound of the formula I: ##STR1## wherein R.sup.1 indicates a phenyl group which may be substituted or an aralkyl group having 7 to 10 carbon atoms which may be substituted, and R.sup.2 indicates an alkyl group having 1 to 6 carbon atoms, which is characterized by contacting a cutlture of a microorganism belonging to Arthrobacter having an ability to preferentially metabolize one optical isomer based on an asymmetric carbon atom to which an amino group bonds in the amine compound of the formula I or a treated product thereof with the amine compound of the formula I.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.