Therapeutic Quassinoid preparations with antineoplastic, antiviral, and herbistatic activity
US5965493A · kind A · utility
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42Claims
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Key dates
| Filing date | May 1, 1997 |
| Grant date | Oct 12, 1999 |
| Priority date | — |
| Expiry date | May 1, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention includes purified and isolated quassinoids and synthetically derived quassinoid analogs based on a picrasane carbon skeleton. Novel sidechains at C-15 incorporating water solubilizing agents such as glycine are discussed. Therapeutic methods taking advantage of anticancer, antiviral, and herbistatic properties of these quassinoids are disclosed, including use against solid tumors and human immunodeficiency virus infected cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.