Prodrugs of thrombin inhibitors
US5965692A · kind A · utility
19Cited by
20References
38Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 31, 1997 |
| Grant date | Oct 12, 1999 |
| Priority date | — |
| Expiry date | Jan 31, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
There is provided compounds of formula I, EQU R.sup.1 O(O)C--CH.sub.2 --(R)Cgl-Aze-Pab-R.sup.2 I wherein R.sup.1 and R.sup.2 have meanings given in the description, which are useful as prodrugs of inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (eg thrombosis) or as anticoagulants.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.