System for prediction of life-threatening cardiac arrhythmias

US5967995A · kind A · utility

Assignee

• University of Pittsburgh—Of the Commonwealth System of Higher Education · US

Inventors

• Vladimir Shusterman · Pittsburgh, US
• Benhur Aysin · Bensalem, US
• Ilan Grave · Pittsburgh, US
• Luis F. Chaparro · Monroeville, US
• Kelley P. Anderson · Dorpsstraat, US

Key dates

• Filing date: Apr 28, 1998
• Grant date: Oct 19, 1999
• Expiry date: Apr 28, 2018

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61B5/726
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A medical device and method for predicting life-threatening cardiac arrhythmias (LTCA) by gathering electrocardiographic data such as intervals between heart beats (RR-series) or other signal, mathematically decomposing or compressing the signal into several elements or components that contain the most significant information and tracking the changes in the several elements. The signal may be divided into time windows, and the signals decomposed into a plurality of coefficients or components such as Karhunen Loeve Transformation (KLT) coefficients that are predictive of the occurrence of LTCA. The electrocardiographic data may be generated real-time, on-line, or be prerecorded data.