Polymers with controlled physical state and bioerodibility
US5968543A · kind A · utility
91Cited by
20References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 5, 1997 |
| Grant date | Oct 19, 1999 |
| Priority date | — |
| Expiry date | Dec 5, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/91
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Polymers useful as orthopedic implants or vehicles for the sustained delivery of pharmaceutical, cosmetic and agricultural agents are prepared in such a manner that the rate and degree to which they are hydrolyzed can be controlled without addition of exogenous acid. This control results from the incorporation of esters of short-chain .alpha.-hydroxy acids such as esters of glycolic acid, lactic acid or glycolic-co-lactic acid copolymer into the polymer chain and variation of the amount of these esters relative to the polymer as a whole.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.