Methods for determining T-cell profiles of immunocompromised subjects
US5968755A · kind A · utility
25Cited by
2References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 26, 1996 |
| Grant date | Oct 19, 1999 |
| Priority date | — |
| Expiry date | Sep 26, 2016 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/56972
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of identifying an abnormal T-cell profile of an immunocompromised subject is disclosed. The method involves detecting the immunoreactivity of T-cells with at least two antibodies selectively reactive with naive T-cell surface proteins and comparing data from cells isolated from an immunocompromised subject with data from cells isolated form a non-immunocompromised subject. Also disclosed are methods of screening drugs or compounds for efficacy to stimulate the production of naive T cells in a subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.