Method for magnetically separating cells into fractionated flow streams
US5968820A · kind A · utility
91Cited by
13References
27Claims
0Family size
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Key dates
| Filing date | Feb 26, 1997 |
| Grant date | Oct 19, 1999 |
| Priority date | — |
| Expiry date | Feb 26, 2017 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N15/149
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for separating cells is presented. The method provides a flow through fractional cell sorting process that is based on the application of a magnetic force to cells having a range of magnetic labeling densities. Magnetically labeled cells are introduced into a flow channel. The cells are continuously fractionated into flow streams based on magnetic susceptibility by subjecting the cells in the flow channel to a magnetic field. The fractionated cells are recovered based on their response to the magnetic field. Methods employing dipole fractional sorters and quadrapole annular sorters are also presented.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.