Reagent for measurement of leukocytes and hemoglobin concentration in blood
US5968832A · kind A · utility
18Cited by
10References
4Claims
0Family size
Assignee
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Key dates
| Filing date | Apr 8, 1998 |
| Grant date | Oct 19, 1999 |
| Priority date | — |
| Expiry date | Apr 8, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/2525
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A reagent for measurement of leukocytes and hemoglobin concentration in the blood includes a cationic surfactant in an amount sufficient to lyse erythrocytes and denature hemoglobin, at least one of the following hemoglobin stabilizers: PA1 (a) sulfosalicylic acid, or its salt, in an amount effective for promoting the conversion of hemoglobin into methemoglobin, PA1 (b) 0.2 to 10.0 g/L of a water-soluble chelating agent having a nitrogen atom and a carboxyl group, and PA1 (c) piperazine, or its salt, in an amount effective for promoting the conversion of hemoglobin into methemoglobin, and a buffer for maintaining pH at 4 to 6.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.