Patent · US Expired

Retinoid suppression of ventricular muscle cell hypertrophy

US5968981A · kind A · utility

5Cited by
2References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 10, 1998
Grant dateOct 19, 1999
Priority date
Expiry dateMar 10, 2018

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N33/9453
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A method of suppressing ventricular muscle cell hypertrophy induced by an .alpha..sub.1 -adrenergic agonist or endothelin, by providing an effective amount of a retinoic acid compound. Also provided are methods for identifying compounds which suppress ventricular muscle cell hypertrophy, compounds which inhibit the retinoic acid suppression of ventricular muscle cell hypertrophy, and therapeutic methods.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.