Helicobacter pylori nickel binding protein
US5972348A · kind A · utility
1Cited by
9References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 14, 1998 |
| Grant date | Oct 26, 1999 |
| Priority date | — |
| Expiry date | Jul 14, 2018 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/205
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The application discloses a nickel binding protein and its encoding DNA isolated from Helicobacter pylori. This organism is the primary cause of chronic gastritis and ensuing peptic ulcers, and has been implicated in stomach cancer. The nickel binding protein is useful to inhibit assembly of active ureases, the enzymes responsible for the pathogenic features of the bacterium. Potential uses include as a vaccine, a diagnostic, a drug target, and a therapy in itself.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.