Solid solution of an antifungal agent with enhanced bioavailability
US5972381A · kind A · utility
29Cited by
1References
2Claims
0Family size
Assignee
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Key dates
| Filing date | Jun 25, 1997 |
| Grant date | Oct 26, 1999 |
| Priority date | — |
| Expiry date | Jun 25, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/146
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A pharmaceutical composition in the form of a substantially amorphous solid solution comprising an antifungal compound of the formula I: ##STR1## wherein: X is F; and R.sub.1 is ##STR2## or an ester or ether of said compound of Formula I; and a soluble or insoluble polymer such as: povidone or crospovidone, wherein the ratio of said compound to said polymer is about 1:3 to about 1:6 is disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.