DNA strands useful for the synthesis of xanthophylls and the process for producing the xanthophylls
US5972690A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Jan 13, 1998 |
| Grant date | Oct 26, 1999 |
| Priority date | — |
| Expiry date | Jan 13, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P23/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed are the following DNA strands relating to the synthesis of keto group-containing xanthophylls such as astaxanthin and the like, and the techniques relating to the production of xanthophylls by genetic engineering: PA1 A DNA strand having a nucleotide sequence which encodes a polypeptides having and enzyme activity for converting a methylene group at the 4-position of a .beta.-ionone ring into a keto group. PA1 A DNA strand having a nucleotide sequence which encodes a polypeptide having an enzyme activity for converting a methylene group at the 4-position of a 3-hydroxy-.beta.-ionone ring into a keto group. PA1 A DNA strand having a nucleotide sequence which encodes a polypeptide having an enzyme activity for adding a hydroxyl group to the 3-carbon of a 4-keto-.beta.-ionone ring. It is possible to produce a variety of xanthophylls such as canthaxanthin, astaxanthin and the like by introducing the DNA strands into an appropriate microorganism such as Escherichia coli and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.