Gene delivery system
US5972707A · kind A · utility
38Cited by
9References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 9, 1997 |
| Grant date | Oct 26, 1999 |
| Priority date | — |
| Expiry date | Jul 9, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A gene delivery system is made of enzymatically degradable polymeric cation and nucleic acid (DNA or RNA) nanospheres optionally with a linking moiety or a targeting ligand attached to the surface. The delivery system can be made by a simple method of coacervation. Targeting ligands can be attached to the nanosphere directly or via a linking moiety. The linkage design allows the attachment of any molecule onto the nanosphere surface including antibodies, cell adhesion molecules, hormones and other cell-specific ligands.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.