Synthetic peptides for arterial imaging
US5972890A · kind A · utility
42Cited by
4References
46Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 28, 1995 |
| Grant date | Oct 26, 1999 |
| Priority date | — |
| Expiry date | Feb 28, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Vascular disease including asymptomatic atherosclerosis can be diagnosed by administering a synthetic peptide or peptide analog having an affinity for, and propensity to accumulate at, a site of vascular injury to a patient, and then detecting the location of the peptide or peptide analog within the patient's vascular system. The synthetic peptide or peptide analog may include an amino acid sequence sufficiently duplicative of the amino acid sequence of a region of either the apolipoprotein B, apolipoprotein A-I, or elastin proteins such that the peptide or peptide analog accumulates at a site of vascular injury.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.