Neuroprotective pharmaceutical composition containing stereoisomers of arylcyclohexylamines
US5972952A · kind A · utility
3Cited by
4References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 10, 1996 |
| Grant date | Oct 26, 1999 |
| Priority date | — |
| Expiry date | Dec 10, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/445
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to pharmaceutical compositions for neuroprotection containing the compound (1S,2R) 1-[1-(2-thienyl)-2-alkylcyclohexyl]piperidine or (1S,2R) 1-[1-(2-furanyl)-2-alkylcyclohexyl]piperdine, or their pharmaceutically acceptable salts. The synthesis and method separation of racemic mixtures to provide pure enantiomers is presented. The compositions have use in the treatment of stroke, CNS trauma and Alzheimer's disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.