Patent · US Expired

Benzimidazole, benzoxazole and benzothiazole compounds

US5972968A · kind A · utility

14Cited by
2References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 23, 1997
Grant dateOct 26, 1999
Priority date
Expiry dateJul 23, 2017

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D403/12
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A compound of formula (I): ##STR1## in which: R.sub.1 represents halogen or hydroxyl, alkoxy, trihalomethyl, amino, mercapto, alkylthio, trialkylammonium, aryloxy, arylthio, arylsulfonyl, arylsulfonyloxy, cycloalkyloxy, cycloalkylthio, bicycloalkyloxy or bicycloalkylthio, PA1 R.sub.a and R.sub.b, which may be identical or different, represent hydrogen or alkyl, PA1 X represents oxygen or sulfur or NR, PA1 Y represents the group as defined in the description, PA1 R.sub.2 represents an optionallly substituted aryl, its optical isomers as well as its addition salts with a pharmaceutically acceptable acid or base and medicinal products containing the same are useful as interleukin-1.beta. inhibitor.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.