Fluoro-substituted benzoylpropionic acid derivatives

US5973006A · kind A · utility

Assignee

• Pharmacia & Upjohn S.p.A. · IT

Inventors

• Mario Varasi · Milano, IT
• Antonio Giordani · Pavia, IT
• Carmela Speciale · Nerviano, IT
• Massimo Cini · Milano, IT
• Alberto Bianchetti · Milano, IT

Key dates

• Filing date: Apr 20, 1998
• Grant date: Oct 26, 1999
• Expiry date: Apr 20, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C237/20
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A fluoro-substituted benzoylpropionic acid compound of formula (I) either as a single optical isomer or as a mixture of optical isomers ##STR1## wherein R is hydroxy, amino, hydroxylamine, --OR', --NHR', N(R').sub.2 or --NHOR' in which R' is C.sub.1 -C.sub.6 alkyl or benzyl; or a pharmaceutically acceptable salt thereof.