Polyethylene oxides having saccharide residue at one end and different functional group at another end
US5973069A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 18, 1997 |
| Grant date | Oct 26, 1999 |
| Priority date | — |
| Expiry date | Dec 18, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2985
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides a heterotelechelic oligomer or polymer which is represented by the following formula: ##STR1## wherein A denotes a sugar residue, L denotes a linkage group represented by the following formula ##STR2## wherein R.sup.1 and R.sup.2 independently denote lower alkyl, aralkyl or aryl, PA1 X denotes a single bond or --CH.sub.2 CH--, Z denotes a group forming an unsaturated ester or ether, or a functional group such as halogen which binds to --CH.sub.2 CH.sub.2 --, n denotes an integer of 5-10,000, and m denotes an integer of 0 or 2-10,000. This invention also provides a process to produce the above oligomer or polymer, and further a high molecular-micelle with use of a polyethylene oxide-polyester block polymer which has a sugar residue at its terminal. Said oligomer or polymer is expected to exhibit excellent bioavailability, and is also expected to be utilized in the field such as carriers for drug delivery or diagnostic reagents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.