Intermediates for making benzothiazolone derivatives

US5973167A · kind A · utility

Assignee

• Astra Pharmaceuticals Limited. · GB

Inventors

• Roger Bonnert · Loughborough, GB
• Roger Brown · Coalville, GB

Key dates

• Filing date: Sep 2, 1998
• Grant date: Oct 26, 1999
• Expiry date: Sep 2, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A compound of formula I, including optical isomers thereof, ##STR1## wherein X represents --SO.sub.2 NH-- or --NHSO.sub.2 --, PA1 p, q and r independently represent 2 or 3, PA1 Y represents thienyl optionally substituted by alkyl or halogen, or phenylthio- or phenyl optionally substituted by alkyl or halogen, and each R independently represents H or alkyl, and pharmaceutically acceptable salts, esters and amides thereof