Multiple-probe diagnostic sensor
US5976466A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 15, 1992 |
| Grant date | Nov 2, 1999 |
| Priority date | — |
| Expiry date | Apr 15, 2012 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2291/106
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
There is disclosed a diagnostic sensor device comprising a plurality of sensor probes, a detection device, and a computer for analyzing the signals generated from each sensor probe by multivariate statistical analysis. The plurality of sensor probes comprise a substrate that allows transmission of a signal and a partially selective surface coating the substrate wherein the partially selective surface binds proteins from a biological fluid by multiple, noncovalent interactions, and with the proviso that the partially selective surfaces of each sensor probe in the diagnostic sensor device be different. The diagnostic sensor device can be used as a method for diagnosing disease states in humans and animals, wherein the disease states are characterized by altered protein character and behavior of a biological fluid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.