Expression and secretion of heterologous polypeptides from caulobacter
US5976864A · kind A · utility
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14Claims
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Key dates
| Filing date | Mar 12, 1996 |
| Grant date | Nov 2, 1999 |
| Priority date | — |
| Expiry date | Mar 12, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/20022
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
DNA constructs are provided which code for at least the extreme C-terminal amino acids of the rsaA protein of Caulobacter crescentus fused with heterologous polypeptides. Baterial cells containing, or which express the DNA constructs and secrete the resulting protein are also provided. Chimeric proteins including the C-terminal amino acids of the rsaA protein are provided, including chimeric proteins comprising antigenic epitopes of the Infectious Hematopoietic Necrosis Virus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.