Nucleic acid sequences controlling lung cell-specific gene expression
US5976873A · kind A · utility
4Cited by
3References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 17, 1995 |
| Grant date | Nov 2, 1999 |
| Priority date | — |
| Expiry date | May 17, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2984
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An oligonucleotide which includes at least one nucleic acid sequence which binds to at least one nuclear protein found in lung cells, such as TTF-1 protein. The oligonucleotide may be contained in a vector. The at least one nuclear protein provides for lung cell-specific expression of the vector upon binding of the at least one nucleic acid sequence to the at least one nuclear protein. Such vector may also include genes encoding therapeutic agents, and may be employed for delivering genes encoding therapeutic agents to lung cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.