Pharmaceutical compositions for the nasal delivery of compounds useful for the treatment of osteoporosis
US5977070A · kind A · utility
82Cited by
25References
13Claims
0Family size
Inventors
Key dates
| Filing date | Aug 29, 1995 |
| Grant date | Nov 2, 1999 |
| Priority date | — |
| Expiry date | Aug 29, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A pharmaceutical composition for the nasal delivery of compounds useful for treating osteoporosis, comprising an effective amount of a physiologically active truncated analog of PTH or PTHrp, or salt thereof, in which amino acid residues (22-31) form an amphipathic .alpha.-helix, said residues (22-31) selected from (SEQ ID NOS: 85, 86, 26, 27, 28, 29, and 30); an absorption enhancer selected from the group consisting of dimethyl-.beta.-cyclodextrin and the bile acid surfactants; and water is provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.