Self-assembling polynucleotide delivery method
US5977084A · kind A · utility
37Cited by
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49Claims
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Inventors
Key dates
| Filing date | Jun 7, 1995 |
| Grant date | Nov 2, 1999 |
| Priority date | — |
| Expiry date | Jun 7, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G2261/312
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides a self-assembling polynucleotide delivery system comprising components aiding in the delivery of the polynucleotide to the desired address which are associated via noncovalent interactions with the polynucleotide. The components of this system include DNA-masking components, cell recognition components, charge-neutralization and membrane-permeabilization components, and subcellular localization components. Specific compounds useful in this system are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.