Isoxazole and crotonamide derivatives and their use as pharmaceuticals and diagnostics

US5977151A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Stefan Mullner · Langenfeld, DE
• Bernd Kirschbaum · Mainz, DE
• Wilfried Schwab · Altentreptow, DE

Key dates

• Filing date: Jan 23, 1998
• Grant date: Nov 2, 1999
• Expiry date: Jan 23, 2018

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/94
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A compound of the formula ##STR1## where R.sup.1 is the radical of the formula II or III ##STR2## is suitable for the production of a pharmaceutical for the treatment of inflammations, carcinomatous diseases, or autoimmune diseases. A compound of the formula IV ##STR3## is suitable for the production of specific antibodies against a compound of the formula I for the discovery of specific-binding proteins from cell extracts, serum, blood, or synovial fluids, for the purification of proteins, for the modification of microtiter plates, or for the preparation of chromatography material, in particular of affinity chromatography material, and for use in diagnostics.