Patent · US Expired

PGE.sub.1 -containing-freeze dried preparation and process for the production thereof

US5977172A · kind A · utility

19Cited by
3References
33Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 12, 1998
Grant dateNov 2, 1999
Priority date
Expiry dateMar 12, 2018

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K31/557
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The object of the invention is to provide a high-quality pharmaceutical preparation in the field of PGE.sub.1 -containing fat emulsions, which is more stable bacteriologically, thermally, and against aging than any preparation hereto fore available. The invention, thus, relates to a PGE.sub.1 -containing lyophilized composition derived from a fat emulsion comprising PGE.sub.1, an oil component, an emulsifier, and water having a pH controlled within the neutral region. Stated differently, the invention relates to a PGE.sub.1 -containing lyophilized composition characterized by comprising PGE.sub.1, an oil component, an emulsifier and designed to give a fat emulsion having a pH within the neutral region upon reconstitution with distilled water of pH 7.0.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.