Platelet substitutes and conjugation methods suitable for their preparation
US5977313A · kind A · utility
21Cited by
4References
28Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 17, 1997 |
| Grant date | Nov 2, 1999 |
| Priority date | — |
| Expiry date | Oct 17, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P7/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Platelet substitutes, comprising fibrinogen, or analogous products useful in therapy, which further comprise an insoluble carrier to which is bound an essentially non-degraded active protein including the sequence Arg-Gly-Asp. Such conjugates can be made by a conjugation process comprising 0.01 to 2.5% by weight active fibrinogen, and no more that 50% inactive fibrinogen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.