Process for making morphine-6-glucuronide or substituted morphine-6-glucuronide
US5977326A · kind A · utility
33Cited by
3References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 14, 1997 |
| Grant date | Nov 2, 1999 |
| Priority date | — |
| Expiry date | Apr 14, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H15/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
##STR1## Morphine-6-glucuronide or substituted morphine-6-glucuronide of formulae (I) is made by conjugation of a glucuronate ester and/or substituted glucuronate ester with morphine or substituted morphine in the presence of a Lewis acid catalyst and in the absence of silver catalysts and barium hydroxide and other heavy metal derivatives.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.