DNA sequence encoding the myotonic dystrophy gene and uses thereof
US5977333A · kind A · utility
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15Claims
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Key dates
| Filing date | Apr 14, 1995 |
| Grant date | Nov 2, 1999 |
| Priority date | — |
| Expiry date | Apr 14, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A nucleotide sequence, specifically a CTG triplet repeat, is shown to be expanded in individuals affected with myotonic dystrophy and can be identified in a sample obtained from an individual. Individuals in whom the CTG triplet repeat is present in normal copy number are likely to be minimally affected and individuals in whom the CTG triplet repeat occurs in abnormally high copy number are likely to be more severely affected.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.