Micro injector sample delivery system for charged molecules
US5980713A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 29, 1996 |
| Grant date | Nov 9, 1999 |
| Priority date | — |
| Expiry date | Aug 29, 2016 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N27/44743
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A micro injector sample delivery system for charged molecules. The injector is used for collecting and delivering controlled amounts of charged molecule samples for subsequent analysis. The injector delivery system can be scaled to large numbers (>96) for sample delivery to massively parallel high throughput analysis systems. The essence of the injector system is an electric field controllable loading tip including a section of porous material. By applying the appropriate polarity bias potential to the injector tip, charged molecules will migrate into porous material, and by reversing the polarity bias potential the molecules are ejected or forced away from the tip. The invention has application for uptake of charged biological molecules (e.g. proteins, nucleic acids, polymers, etc.) for delivery to analytical systems, and can be used in automated sample delivery systems.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.