Dry analytical element and method for the detection of prostatic acid phosphatase
US5981206A · kind A · utility
5Cited by
21References
18Claims
0Family size
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Key dates
| Filing date | May 20, 1992 |
| Grant date | Nov 9, 1999 |
| Priority date | — |
| Expiry date | May 20, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2334/70
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A dry analytical element has been prepared for the assay of prostatic acid phosphatase at a pH of from about 3 to about 6.5. The element can be a single porous spreading zone or a multilayer structure. Within the element is a relatively nonhygroscopic aromatic phosphate substrate for the analyte which produces a phenol reaction product. This product is reacted with a diazonium or tetrazolium salt, also in the element, to produce a chromophore for detection. A buffer in the element maintains it at the proper pH during the assay.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.