Method and constructs for inhibiting protein expression in bacteria
US5981280A · kind A · utility
15Cited by
1References
41Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 19, 1996 |
| Grant date | Nov 9, 1999 |
| Priority date | — |
| Expiry date | Dec 19, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/111
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method of inhibiting the translation of bacterial mRNA is disclosed, which method comprises overexpressing in a bacterium an mRNA which contains a sequence which is complementary to the anti-downstream box region of the 16S rRNA. RNA and DNA constructs for the overexpression of the mRNA of the invention are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.