Substituted 5-membered ring heterocycles, their preparation and their use

US5981492A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Gerhard Zoller · Blankenloch, DE
• Otmar Klingler · Rodgau, DE
• Bernd Jablonka · Bad Soden, DE
• Melitta Just · Langen, DE
• Gerhard Breipohl · Scheinfeld, DE
• Jochen Knolle · Kriftel, DE
• Wolfgang Konig · Hofheim, DE
• Hans Ulrich Stilz · Frankfurt am Main, DE

Key dates

• Filing date: Jul 19, 1996
• Grant date: Nov 9, 1999
• Expiry date: Jul 19, 2016

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention pertains to 5-ring heterocycles of general formula (I), wherein W, Y, Z, B, D, E and R as well as b, c, d, e, f, g, and h are as indicated in the description; to methods for preparing them, and to their use as inhibitors of platelet aggregation, metastasizing of carcinomatous cells and the attachment of osteoclasts to the bone surface. ##STR1##