RPS gene family, primers, probes, and detection methods

US5981730A · kind A · utility

Assignees

• The General Hospital Corporation · US
• COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION · AU
• The United States of America, as represented by the Secretary of Agriculture · US
• The Regents of the University of California · US

Inventors

• Frederick M. Ausubel · Newton, US
• Brian J. Staskawicz · Castro Valley, US
• Fumiaki Katagiri · San Diego, US
• Barbara Baker · Richmond, US
• Jeffrey Ellis · Belconnen, AU
• John Salmeron · Hillsborough, US

Key dates

• Filing date: Sep 22, 1994
• Grant date: Nov 9, 1999
• Expiry date: Sep 22, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2600/156
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Disclosed is substantially pure DNA encoding an Arabidopsis thaliana Rps2 polypeptide; substantially pure Rps2 polypeptide; and methods of using such DNA to express the Rps2 polypeptide in plant cells and whole plants to provide, in transgenic plants, disease resistance to pathogens. Also disclosed are conserved regions characteristic of the RPS family and primers and probes for the identification and isolation of additional RPS disease-resistance genes.