Knockout mice and their progeny with a disrupted hepsin gene
US5981830A · kind A · utility
27Cited by
0References
17Claims
0Family size
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Inventors
Key dates
| Filing date | Dec 30, 1997 |
| Grant date | Nov 9, 1999 |
| Priority date | — |
| Expiry date | Dec 30, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2217/075
- WIPO fieldOther special machines
- WIPO sectorMechanical engineering
Abstract
The present invention provides a transgenic mouse comprising a disrupted hepsin gene. In particular, the invention provides methods of making the transgenic mouse comprising the disrupted hepsin gene by utilizing a hepsin targeting vector for homologous recombination in mouse embryonic stem cells. Also, nucleotide and amino acid hepsin sequences are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.