Destruction of contaminating tumor cells in stem cell transplants using bispecific antibodies

US5985276A · kind A · utility

Assignee

• GSF FORSCHUNGSZENTRUM FUR UMWELT UND GESUNDHEIT GMBH · DE

Inventors

• Horst Lindhofer · Puchheim, DE
• Helge Menzel · Hersbruck, DE
• Hans-Jochem Kolb · Hersbruck, DE
• Stefan Thierfelder · Eichenau, DE

Key dates

• Filing date: Sep 3, 1997
• Grant date: Nov 16, 1999
• Expiry date: Sep 3, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention discloses a procedure for the destruction of contaminating tumor cells in stem cell transplants ex vivo using intact bispecific antibodies.