Method of preparing a biological glue able to coagulate simply by addition of calcium ions
US5985315A · kind A · utility
71Cited by
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29Claims
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Assignee
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Key dates
| Filing date | Dec 30, 1997 |
| Grant date | Nov 16, 1999 |
| Priority date | — |
| Expiry date | Dec 30, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L24/106
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
By placing a blood plasma in contact with a blood coagulation contact phase activator, before or during preparation of a fibrinogen-based biological glue, a preactivated biological glue is obtained which does not coagulate spontaneously but which is capable of coagulating in less than 5 minutes simply by the addition of calcium ions, without the addition of thrombin. The process has application to the field of surgery.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.