FC receptor for immunoglobulin
US5985599A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 31, 1994 |
| Grant date | Nov 16, 1999 |
| Priority date | — |
| Expiry date | Oct 31, 2014 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/04
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Nucleotide sequences encoding a protein with Fc receptor activity or a fragment thereof that is capable of binding the Fc region of immunoglobulin and polypeptides with Fc receptor activity are provided. Proteins which exhibit enhanced or reduced immunoglobulin binding ability relative to native Fc receptors and nucleotides encoding these proteins also are provided. The invention also provides methods of determining the presence of immunoglobulin, detecting an immune complex, removing immunoglobulin from a body fluid and treating disease using the proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.