"Use of an ""immunodeficiency-virus suppressing lymphokine (ISL) ""to inhibit the replication of viruses, in particular of retroviruses"

US5985613A · kind A · utility

Assignee

• Budresrepublik Deutschland Vertreten Durch Den Bundesminister Fur Gesundheit · DE

Inventors

• Reinhard Kurth · Neu-Isenburg, DE
• Michael Baier · Frankfurt, DE
• Karin Metzner · Frankfurt, DE
• Albrecht Werner · Weinheim, DE

Key dates

• Filing date: Oct 6, 1997
• Grant date: Nov 16, 1999
• Expiry date: Oct 6, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

An isolated polypeptide which inhibits the replication of retroviruses in peripheral blood lymphocytes and i) is encoded by the DNA sequence shown in SEQ ID NO: 1 or complementary sequences; or ii) is encoded by DNA sequences which are degenerate to those of SEQ ID NO: 1 or its complement, and nucleic acids encoding said polypeptide. The protein is useful for inhibition of viral replication.