Method for preventing the activation of inactive, recombinant Helicobacter pylori apourease
US5985631A · kind A · utility
9Cited by
2References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 12, 1997 |
| Grant date | Nov 16, 1999 |
| Priority date | — |
| Expiry date | Sep 12, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for preventing the activation of inactive, recombinant Helicobacter pylori apourease is presented. The method comprises contacting the apourease with a compound that modifies a sulfhydryl or lysyl residue of the urease. The covalently modified apourease is prevented from molecular aggregation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.